The insecticide seed treatment is one of the modern concepts of pest control. However, it must be known the influence of these products on the physiological quality of treated seeds. So, this research was carried out in order to evaluate the effect of the insecticides carbofuran (Furazin 310TS), thiodicarb (Semevin 350 RA), thiodicarb + nutrients Mo and B (Futur 300) and thiamethoxan (Cruiser 70WS) on germination and vigor of corn seed with different storage periods. Corn seeds of Cargill-929 (single hybrid) and Cargill-747 (three way hybrid) were treated with these products, stored under ambient conditions and evaluated at the same day of seed treatment and 15 and 30 days after storage. Germination and vigor tests (electrical conductivity and cold test) were performed. Only the insecticide carbofuran showed some adverse effect on seed germination, being more critical for the three way hybrid seeds. All insecticides caused significant reduction on seed vigor, but this effect was variable according to hybrid, insecticide and storage time. The decrease on the seed physiological quality increased with seed storage. So, it is better if the insecticide seed treatment is done immediately before sowing.